Welcome to the Harrison lab!

Research in the Harrison lab focuses on how information encoded in the genome is differentially interpreted during organismal development. Specifically, we study the molecular mechanisms regulating gene expression and how changes in gene expression can drive cell identity. Because these processes are highly conserved amongst metazoans, we leverage the wide number of tools available to study this regulation in the Drosophila embryo. Current research in the laboratory is primarily directed at understanding the function of proteins that act at the top of gene regulatory networks to elicit dramatic changes in cell fate.

In our lab, we are committed to making science more equitable. We believe that the most innovative science happens within a diverse team and a supportive environment. To this end, we strive to eliminate systemic barriers to the recruitment and retention of underrepresented groups in science.

We are looking for folks to join the lab! Check this out for more information: Postdoc Posting

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News

• We are so proud of the amazing undergraduates working with us in the lab and so pleased that Steven Huang and Zoe Fitzpatrick have been recognized by a Hilldale Fellowship and a Genetics and Genomics Distinguished Undergraduate Fellowship, respectively. Way to go!

• Our paper on the essential role of GAF in early embryonic development is online now at eLife. Way to go Marissa and Tyler.

Recent Publications

•  Gaskill, M.M., Gibson, T.J., Larson, E.D. and Harrison, M.M. (2021) GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo. eLife doi.org/10.7554/eLife.66668

Larson, E.D., Marsh, A.J., and Harrison, M. M. (2021) Pioneering the developmental frontier. Mol Cell doi.org/10/1016/j.molcel.2021.02.020

 more publications…