Welcome to the Harrison lab!
Research in the Harrison lab focuses on how information encoded in the genome is differentially interpreted during organismal development. Specifically, we study the molecular mechanisms regulating gene expression and how changes in gene expression can drive cell identity. Because these processes are highly conserved amongst metazoans, we leverage the wide number of tools available to study this regulation in the Drosophila embryo. Current research in the laboratory is primarily directed at understanding the function of proteins that act at the top of gene regulatory networks to elicit dramatic changes in cell fate.
In our lab, we are committed to making science more equitable. We believe that the most innovative science happens within a diverse team and a supportive environment. To this end, we strive to eliminate systemic barriers to the recruitment and retention of underrepresented groups in science.
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News
• Welcome Haley Brown who joins the lab as a postdoctoral fellow following her impressive PhD at Indiana in Justin Kumar’s lab!
• Excited to share our review “Exploring the reciprocity between pioneer factors and development”. Out now in Development!
Recent Publications
Gibson, T.J., Larson, E.D, and Harrison, M.M. (2024) Protein-intrinsic properties and context-dependent effects regulate pioneer factor binding and function. Nat Struct Mol Biol. doi:10.1038/s41594-024-1231-8